Drew Brees – Questionable: Drew Brees insists he will play against the Jaguars even with a torn plantar fascia. The reality is, fantasy owners need to have a backup ready to roll.
Brian Hoyer – Questionable: Hoyer has been limited all week and hasn’t been cleared from his concussion; expect Brandon Weeden to get the start against the Titans.
Adrian Peterson – Probable: Adrian Peterson will play against the Giants after a full week of practice despite an ankle injury.
LeSean McCoy – Out: McCoy will not play against the Dallas Cowboys; expect Karlos Williams and Mike Gillislee to split carries at running back.
T.J. Yeldon – Doubtful: Yeldon will not play against the Saints. Dennard Robinson will get the start and is expected to have a big day.
Shawn Draghn – Out: Draghn will not play against the Lions, expect Kendall Gaskins, Dujuan Harris, and full back Bruce Miller to carry the workload.
Matt Jones – OUT
Tevin Coleman – Out: Tevin Coleman will not play against the Carolina Panthers, fantasy owners can expect Devonta Freeman to start and carry the workload at running back.
Andre Ellington – Questionable: Andre Ellington is expected to play against the Packers according to Bruce Arians and will back up David Johnson.
Alshon Jeffery – Doubtful: Alshon Jeffery most likely will not play; expect Eddie Royal, Marc Mariani, and Josh Bellamy to carry the workload at wide receiver.
Calvin Johnson – Questionable: Calvin Johnson should play against the 49ers after practicing a full week.
Danny Amendola- Questionable: Amendola is NOT expected to play against the Jets during Week 16.
Dwayne Harris – Questionable: Dwayne Harris is expected to play against the Vikings. Fantasy owners can expect Ruben Randle and Hakeem Nicks to carry the workload in Odell Beckham’s absence.
Donte Moncreif: Questionable: Donte Moncreif injured his foot and was limited in practice all week if he cannot play against the Colts, expect Phillip Dorsett to start.
Rishard Matthews – Questionable: Rishard Matthews most likely will not play against the Colts; fantasy owners can expect Devante Parker, Jarvis Landry and Kenny Stills to carry the workload at wide receiver.
Julian Edelman- Doubtful: Julian Edelman will not play against the Jets. Fantasy owners can expect Brandon Lafell to carry the workload at wide receiver along with an uncertain Danny Amendola.
Dez Bryant – Doubtful: Dez Bryant will not play against the Buffalo Bills. Fantasy owners can expect Cole Beasley and Terrance Williams to carry the workload at wide receiver.
Marques Colston – Questionable: Marques Colston most likely will not play against the Jaguars.
Charles Clay – Out: Charles Clay will not play against the Cowboys; expect Chris Gragg and Nick O’Leary to be in rotation at Tight End.
Ben Watson – Questionable: Ben Watson has a knee injury and may not play against the Jaguars. Fantasy owners should have a backup plan just in case he does not suit up.